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Biochemical genetics --- Proteins

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Die Pharmakogenetik untersucht den Einfluss individueller genetischer Merkmale auf Wirkung und unerwünschte Wirkung von Arzneimitteln. Dieses Buch macht auf die Perspektiven der Pharmakogenetik für eine verbesserte Pharmakotherapie aufmerksam und stellt die praxisrelevanten, wichtigen Entwicklungen und Erkenntnisse der Forschung dar. Den Ärzten sollen Möglichkeiten aufgezeigt werden, anhand der Untersuchung genetischer Dispositionen von Patienten die Arzneimittelwirksamkeit zu optimieren und unerwünschte Arzneimittelwirkungen und Interaktionen zu minimieren. This practical work on pharmacogenetics seeks to increase the awareness of primary care physicians ordering diagnostic laboratory tests about the possibilities in pharmacogenetics, to alleviate their fears of approaching this new realm, and to uncover its potential for improving pharmacotherapy.

Pharmacogenetics. --- Pharmacology --- Biochemical genetics --- Genetic aspects

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In the post-genomic era, one of the key challenges for drug discovery is making optimal use of the comprehensive genomic data available after the elucidation of the human genome and others in order to identify effective new medicines. Addressing this challenge, chemogenomics aims to identify systematically all ligands and modulators for all the gene products expressed and allows the accelerated exploration of their biological function. The subject brings together diverse disciplines including chemistry, genetics, chemo- and bioinformatics, structural biology, and biological screening in phenot

Chemogenomics. --- Biochemical genetics. --- Chemical genetics --- Biochemistry --- Molecular genetics --- Chemical genomics --- Genomes --- Biochemical genetics --- Chemicals --- Effect of chemicals on --- Physiological effect

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Genetic toxicology --- Genotoxicity --- Genotoxicology --- Toxicology --- Biochemical genetics --- Medical genetics --- Carcinogenesis --- Chemical mutagenesis --- Genetic aspects

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DNA repair. --- Deoxyribonucleic acid repair --- Repair, DNA --- Repair mechanisms in DNA --- Biochemical genetics --- Antimutagens